Doliprane Uses, Dosage, Side Effects, Precautions & Warnings

Drug Online

What is doliprane used for

Generic drug of the therapeutic class: Analgesics
active ingredients: Paracetamol

What is doliprane used for and  indication?

Symptomatic treatment of mild to moderate pain and / or febrile conditions .

Powder for oral solution:

  • 100 mg sachet: This presentation is reserved for children from 6 to 20 kg(approximately 3 months to 7 years).
  • Sachet 150 mg: This presentation is reserved for children from 8 to 30 kg(about 6 months to 11 years).
  • 200 mg sachet: This presentation is reserved for children from 11 to 25 kg(approximately 18 months to 10 years).
  • 300 mg sachet: This presentation is reserved for children from 16 to 48 kg(approximately 4 to 15 years old).

Suppository:

  • Suppository 100 mg: This presentation is reserved for infants weighing 3 to 8 kg(approximately from birth to 9 months).
  • Suppository 150 mg: This presentation is for infants weighing 8 to 12 kg(approximately 6 to 24 months).
  • Suppository 200 mg: This presentation is reserved for children weighing 12 to 16 kg(about 2 years to 5 years).
  • Suppository 300 mg: This presentation is reserved for children weighing 15 to 24 kg(about 4 years to 9 years).

doliprane dosage in english

Administration mode

Oral way.

  • The capsules are swallowed as is with a drink (eg water, milk, fruit juice).
  • Capsule taking is contraindicated in children under 6 years of age because it can lead to a wrong course. Use another form.

Dosage

  • This presentation is reserved for adults and children from 27 kg (approximately from 8 years old).
  • In children, it is imperative to respect the dosages defined according to the weight of the childand therefore to choose a suitable presentation. Approximate ages by weight are given for information.
  • The recommended daily dose of paracetamol is approximately 60 mg / kg / day, to be divided into 4 or 6 doses, approximately 15 mg / kg every 6 hours or 10 mg / kg every 4 hours.
  • For children weighing 27 to 40 kg (approximately 8 to 13 years), the dosage is 1 capsule 500 mg per dose, to be renewed if necessary after 6 hours, without exceeding 4 capsules per day.
  • For children weighing 41 to 50 kg (approximately 12 to 15 years), the dosage is 1 capsule 500 mg per dose, to be renewed if necessary after 4 hours, without exceeding 6 capsules per day.
  • For adults and children weighing more than 50 kg (from about 15 years old);
  • The usual unit dosage is 1 to 2 capsules at 500 mg per dose, to be renewed if necessary after a minimum of 4 hours.
  • It is generally not necessary to exceed 3 g of paracetamol per day, or 6 capsules per day. However, in case of more intense pain, the maximum dosage can be increased up to 4 g per day, or 8 capsules per day.
  • Always observe a 4 hour interval between shots.

Maximum recommended doses : see section Warnings and precautions for use .

Frequency of administration

Systematic catches prevent pain or fever oscillations:

  • In children, they should be regularly spaced, including at night , preferably 6 hours , and at least 4 hours.
  • In adults, they must be spaced at least 4 hours apart.

Renal failure

  • In severe renal impairment (creatinine clearance <30 ml / min), the interval between two doses should be increased to at least 8 hours .
  • The dose of paracetamol should not exceed 3 g per day, ie 6 capsules.
  • The lowest effective daily dose should be considered, not to exceed 60 mg / kg / day (not to exceed 3 g / day) in the following situations:
  1. Adults under 50 kg
  2. Mild to moderate hepatocellular insufficiency
  3.   Chronic alcoholism
  4. Chronic malnutrition
  5.  Dehydration

How it works Doliprane?

OTHER ANALGESICS and ANTIPYRETICS-ANILIDES , ATC Code: N02BE01 . N: Central nervous system .

Paracetamol has a central and peripheral mechanism of action.

Doliprane Side Effects

  • Few cases of hypersensitivity reactions such as anaphylactic shock, angioedema, erythema, urticaria, skin rash have been reported.
  • Their occurrence requires the definitive discontinuation of this drug and related drugs.
  • Very exceptional cases of thrombocytopenia, leukopenia and neutropenia have been reported.

Doliprane Interactions

Symptomatic treatment of mild to moderate pain and / or febrile conditions.
Powder for oral solution:

  • 100 mg sachet: This presentation is reserved for children from 6 to 20 kg(approximately 3 months to 7 years).
  • Sachet 150 mg: This presentation is reserved for children from 8 to 30 kg (about 6 months to 11 years).
  • 200 mg sachet: This presentation is reserved for children from 11 to 25 kg (approximately 18 months to 10 years).
  • 300 mg sachet: This presentation is reserved for children from 16 to 48 kg (approximately 4 to 15 years old).

Suppository:

  • Suppository 100 mg: This presentation is reserved for infants weighing 3 to 8 kg (approximately from birth to 9 months).
  • Suppository 150 mg: This presentation is for infants weighing 8 to 12 kg(approximately 6 to 24 months).
  • Suppository 200 mg: This presentation is reserved for children weighing 12 to 16 kg (about 2 years to 5 years).
  • Suppository 300 mg: This presentation is reserved for children weighing 15 to 24 kg (about 4 years to 9 years).

Doliprane Warnings and Precautions

Doliprane Warnings

  • To avoid a risk of overdose,
  •  To check the absence of paracetamol in the composition of other medicinal products
  •   Respect the maximum recommended doses

Maximum recommended doses :

  •  In children under 40 kg , the total dose of paracetamol should not exceed 80 mg / kg / day (see section Overdose ).
  • In children between 41 and 50 kg , the total dose of paracetamol should not exceed 3 g per day (see section  Overdose ).
  •  In adults and children over 50 kg , the total dose of PARACETAMOL SHOULD NOT EXCEED 4 GRAMS PER DAY .
  • The tablet or capsule is contraindicated in children under 6 years of age because it can lead to a miscarriage.

Precautions for use

  • In a child treated with 60 mg / kg / day paracetamol, the combination of another antipyretic is justified only in case of ineffectiveness.
  • Paracetamol should be used with caution in case of:
  1.  weight <50kg
  2. mild to moderate hepatocellular insufficiency
  3. severe renal insufficiency (creatinine clearance £ 30ml / min (see sections Posology and method of administration   and Pharmacokinetic properties ),
  4. chronic alcoholism,
  5. chronic malnutrition (low liver glutathione reserves),
  6. Dehydration (see section Dosage and method of administration )

If acute viral hepatitis is found, treatment should be discontinued

Drive and use machines

Not applicable.

Doliprane and PREGNANCY / BREAST FEEDING / FERTILITY

doliprane during pregnancy

  • Studies in animals have not shown any teratogenic or foetotoxic effect of paracetamol.
  • Clinically, the results of epidemiological studies seem to exclude a particular malformative or fetotoxic effect of paracetamol.
  • As a result, paracetamol, under normal conditions of use, may be prescribed throughout pregnancy.

feeding

  • At therapeutic doses, administration of this drug is possible during breastfeeding.

What happens if I overdose from Doliprane ?

  • The risk of severe intoxication may be particularly high in the elderly, in young children, in patients with liver injury, in case of chronic alcoholism, in patients suffering from chronic malnutrition.
  • In these cases, intoxication can be fatal.

sYMPTOMS

  • Nausea, vomiting, anorexia, pallor, abdominal pain usually appear in the first 24 hours.
  • Overdose, starting with 10 g of paracetamol in a single dose in adults and 150 mg / kg of body weight in a single dose in children, causes hepatic cytolysis which may result in complete and irreversible necrosis Hepatocellular insufficiency, metabolic acidosis, encephalopathy that can lead to coma and death.
  • At the same time, there is an increase in hepatic transaminases, lactic dehydrogenase, bilirubin and a decrease in the prothrombin level that may occur 12 to 48 hours after ingestion.

Emergency driving

  • Immediate transfer to hospital.
  • Collect a tube of blood to do the initial plasma paracetamol test.
  •  Rapid evacuation of the ingested product by gastric lavage.
  • The treatment of overdose typically comprises the administration as early as possible of the antidote N-acetylcysteine ​​IV or oral route if possible before the tenth hour.
  •  Symptomatic treatment.

What is  Forms and Composition?

 Doliprane powder for oral solution:

  • Powder for oral solution at 100, 150, 200 and 300 mg:  sachets-dose, boxes of 12.
  • Doliprane suppository: Suppository breakable 100 mg:  Box of 10, under blister packs.
  • Suppositories at 150, 200 and 300 mg:   Boxes of 10, under blister packs.

NOT’s

Edrug-online contains comprehensive and detailed information about drugs available in the medical field, and is divided into four sections:

general information:

  • Includes a general description of the drug, its use, brand names, FAQs, and relevant news and articles

Additional information:

  • General explanation about dealing with the medicine: how to take the medicine, the doses and times of it, the start and duration of its effectiveness, the recommended diet during the period of taking the medicine, the method of storage and storage, recommendations in cases for forgetting the dose and instructions to stop taking the drug and take additional doses.

Special warnings:

  • For pregnant and breastfeeding women, the elderly, boys and drivers, and use before surgery.

Side effects:

  • It treats possible side effects and drug interactions that require attention and its effect on continuous use.
  • The information contained in this medicine is based on medical literature, but it is not a substitute for consulting a doctor.

The post Doliprane Uses, Dosage, Side Effects, Precautions & Warnings appeared first on Drug Online.



from Drug Online
https://bit.ly/2PaQwSx
via Edrug Online

Comments

Post a Comment

Popular posts from this blog

brufen tablet 400 Uses, Dosage, Side Effects, Composition

Image
Drug Online brufen tablet >> Generic drug of the therapeutic class:  Analgesics active ingredients: Ibuprofen what is brufen tablets? Ibuprofen stills pain,  inhibits inflammation  and lowers fever. In different types of pain and inflammation, such as  joint pain  (  gout  , rheumatoid arthritis, Bechterew’s disease,  osteoarthritis  ), headache,  migraine  , menstruation problems and muscle pain. Also with flu and colds. Regular tablets,  capsules  , drinks and granules work after 30 to 60 minutes. The operation lasts for 8 hours. Delayed-release tablets and suppositories work after 2-3 hours, approximately 12 hours. Note: chances of gastrointestinal ulcers and bleeding. Are you over 70 years of age, have you previously had a stomach or intestinal ulcer or are you using anti-coagulation medication? Then you need a  stomach protector  . Ask your doctor or pharmacist....
Read more

Atarax medicine Uses, Dosage, Side Effects, Precautions

Image
Drug Online atarax medication >> Generic drug of the Therapeutic class: Allergology active ingredients: Hydroxyzine what is atarax medicine? This medicine is recommended in minor manifestations of anxiety, in premedication before general anesthesia, in urticaria, as well as in the treatment of certain insomnia in children over 6 years. Atarax Hydroxyzine what is the drug atarax used for and indication? Minor manifestations of anxiety in adults. Premedication to general anesthesia. Symptomatic treatment of urticaria. In children over 3 years (syrup) or 6 years (tablet), second-line treatment of sleep insomnia related to a state of hyper-arousal (increased vigilance related to anxiety at bedtime), after failure of behavioral measures alone. atarax dosage The tablet is not a form suitable for children under 6 years (risk of mis-driving). Oral way. Atarax Hydroxyzine Uses, Dosage, Side Effects, Precautions atarax dose for adults Minor manifestations ...
Read more

ixprim reviews Uses, Dosage, Side Effects, Precautions & Warnings

Image
Drug Online ixprim reviews >> Generic drug of the therapeutic class: Analgesics active ingredients: Tramadol , Paracetamol what is ixprim ? IXPRIM is a combination of 2 analgesics, tramadol and paracetamol, which work together to relieve your pain. IXPRIM is indicated for the treatment of moderate to severe pain when your doctor thinks that a combination of tramadol and paracetamol is needed. IXPRIM is reserved for adults and adolescents from 12 years old. what are ixprim tablets for and indication ? Symptomatic treatment of moderate to severe pain. The use of Ixprim should be limited to patients whose moderate to severe pain requires treatment with a combination of paracetamol and tramadol ( see Pharmacodynamics ). IXPRIM Dosage Dosage RESERVED FOR ADULTS and ADOLESCENTS (from 12 years old). The use of IXPRIM should be limited to patients with moderate to severe pain requiring treatment with a combination of paracetamol and tramadol hydrochloride. ...
Read more